International Journal of Sport, Exercise and Health Research 2019; 3(1): 14-18 DOI:10.31254/sportmed.3104

Research Article

Influence of Altitude Training on Brain Natriuretic Peptide and Atrial Natriuretic Peptide in Japanese Collegiate Swimmers

Koichi Watanabe¹ , Subrina Jesmin¹ , Tsuyoshi Takeda² , Takahisa Shiraki³ , Yasuo Sengoku¹

Koichi Watanabe,Subrina Jesmin,Tsuyoshi Takeda,Takahisa Shiraki,Yasuo Sengoku

1. Faculty of Health and Sport Sciences, University of Tsukuba, Ibaraki, Japan
2. Juntendo University, Japan
3. Department of Law, Toyo University, Japan

*Author to whom correspondence should be addressed.

Received: 27th May, 2019 / Accepted: 9th July, 2019

Abstract

Objective and method: To examine the effect of altitude swimming training on BNP (Brain natriuretic peptide) and ANP (Atrial Natriuretic Peptide) levels, and evaluate if BNP and ANP can be hemodynamic markers of hypoxia- and traininginduced stress, Ten collegiate swimmers (Tr) who participated in the altitude training camp at 1900m and 5 healthy subjects (Con) were participated in this study. Blood samples were obtained before the training (day0: Pre), during the training (day5: T1, 10: T2, 16: T3), and after the training (5th after descent: Post). Results: Chronologically, BNP of Tr decreased immediately after ascent and increased thereafter, however the changes were not significant. ANP levels were almost unchanged in Tr, whereas there was an increase at T1 in Con compared with Tr (P<0.05). BNP/ANP ratio was significantly higher in Tr (P<0.05) than Con at T3. The results of our study indicate that swimming training at an altitude of 1900m may influence ANP and BNP in the different way, and the stimuli of training is dominant to the hypoxic stress. Conclusion: Our results suggest that we can evaluate the training and hypoxic stress based on natriuretic peptide levels, and predict the hemodynamics or dehydration state by monitoring the natriuretic peptide levels during altitude training.